ARAP3 Antibody, Biotin conjugated

1. Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3. PMID: 27311713
2. structural and binding affinity between odin and arap3 PMID: 23239578
3. Phosphoinositide 3-OH kinase (PI3K) is input into the regulation of beta2 integrin activity, and processes dependent on its responses, by signaling through its effector ARAP3. PMID: 23180820
4. The structural basis for the interaction between Arap3 and Vav2, hydrophobic pockets and binding specificity. PMID: 22750419
5. ARAP3 is a unique Src substrate that suppresses peritoneal dissemination of scirrhous gastric carcinoma cells. PMID: 21076469
6. None of the individual PH domains can bind to PtdIns(3,4,5)P3; rather, a fragment comprising two PH domains and an N-terminal linker is minimally required for binding. PMID: 19786092
7. The catalytic domain of ARF-GAP alone is sufficient to initiate uncoating of liposome-derived COPI-coated vesicles. ARF-GAP activity is not required for COPI coat assembly & does not seem to be an essential coat component of COPI vesicles. PMID: 12832619
8. ARAP3 has a role in integrin-mediated tyrosine kinase signalling pathways controlling Rho GTPases and cell spreading PMID: 15546919
9. ARAP3 deficiency produced by antisense expression of an ARAP3 EST impaired entry of anthrax PA and its bound toxigenic moieties into both human and mouse cells, resulting in reduced toxin sensitivity PMID: 15569923
10. In a yeast two-hybrid screen for new interaction partners of Arap3, the PI 5'-phosphatase SHIP2 was identified as an interaction partner of Arap3. PMID: 17314030

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HGNC: 24097

OMIM: 606647

KEGG: hsa:64411

STRING: 9606.ENSP00000239440

UniGene: Hs.726187